Gm Food Research Paper

Gm Food Research Paper-15
In fact, because genome editing does not introduce foreign DNA into the crop, regulatory agencies are still determining whether plants developed with this technology and the foods from them would be considered GE or not.

In fact, because genome editing does not introduce foreign DNA into the crop, regulatory agencies are still determining whether plants developed with this technology and the foods from them would be considered GE or not.In the cases of certain apples, potatoes, and mushrooms developed with these methods, some regulatory agencies have concluded that safety testing akin to that conducted with foods from GE crops was not necessary (US FDA, March 12, 2015, and March 16, 2015; Waltz, 2016).The segments of interfering RNA can be single-stranded or double-stranded RNA (ds RNA) that activates natural suppression of the RNA by induction of specific ds RNAse or blocking RNA function.

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Furthermore, the genome-edited crops are not yet widely commercialized (Wolt , 2016), and extensive safety data for such crops are not yet available.

Thus, this document focuses on the safety of foods obtained from or produced by the first and second generation GE food crops.

Such genetic modifications are random, not targeted, and usually involve large-scale changes in the plant genome that have not been characterized.

In contrast, genetic engineering involves precise and targeted introduction of a piece of DNA that has been thoroughly characterized and the resulting GE crops characterized using scientifically validated methods (Ladics , 2015).

RNAi is a natural process that combats infection of RNA viruses or controls expression of endogenous gene expression (Eamens , 2008; Vaucheret, 2006).

Methods using RNAi are being investigated for controlling diseases and organisms that attack plants and animals, as well as medicinal control of cancers and metabolic disease as can be seen by searching Pub Med with “RNAi” and “genetic engineering”.

Recent development of advanced genome editing tools, including zinc finger nucleases, TALENs, or CRISPR-Cas9, are providing opportunities to develop what can be described as the next generation of GE crops by introduction of foreign DNA with methods that differ from those described above.

However, these technologies also can be used to cut or make site-specific mutations in endogenous genes (ie, genome editing) without introducing any new DNA into the genome of the plant or by silencing endogenous genes.

This opinion is based on an extensive review of the published scientific literature in which the safety of foods from GE crops has been evaluated.

This document does not address the environmental impact of GE organisms, such as potential gene transfer to nonengineered plants or general environmental impacts of agriculture which have previously been evaluated by economists and ecologists (eg, Brookes and Barfoot, 2013).

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